Does the vet product GenOne Spray cause a burning sensation when spayed on an open wound?

My vet gave me this product to use on my dog's tail.My dog has developed an open wound on his tail near his anus. It started out as either a spider bite, ant bite, bee or wasp sting or a cactus thorn. That's a lot of choices but that is as narrow as we have been able to guess. Every time I spray him, he yelps but I don't know if it really is hurting (burning) him or whether his backside is so sore and sensitive that he's just reacting to something strange and new to him.